Global Advanced Research Journal of Medicine and Medical Sciences (GARJMMS) ISSN: 2315-5159
June 2015 Vol. 4(6), pp. 277-280
Copyright © 2015 Global Advanced Research Journals

Full Length Research Paper

Oral or Intramuscular Vitamin D Replacement?

Mohammad A Mustafa¹ and Ibtisam M Jali²*

¹king Abdulaziz University, Jeddah, Saudi Arabia, medical resident at king Abdulaziz university hospital
²king Abdulaziz University, Jeddah, Saudi Arabia, Assistant professor internal medicine and rheumatology at king Abdulaziz University

*Corresponding Author E-mail: black_shark11323@hotmail.com

Accepted 29 June, 2015

Abstract

Vitamin D deficiency has been shown to be extremely common condition even in sunny climate. We conducted a retrospective analysis on 123 cases to compare oral versus intramuscular cholecalciferol replacement in cases of vitamin D deficiency as well as different doses of intramuscular supplement as assessed by serum levels of total 25 hydroxy vitamin D3. There was a significant increase in vitamin D level after therapy in all regimens (oral, intramuscular 300,000 IU and 600,000 IU). However, the difference in percent change in vitamin D level as a result of therapy was not significant between the 3 groups.

Keywords: Vitamin D deficiency, replacement, cholecalciferol, intramuscular, oral.